GET THE APP

..

Journal of Biometrics & Biostatistics

ISSN: 2155-6180

Open Access

Accelerated Failure Time Models with Auxiliary Covariates

Abstract

Kevin Granville and Zhaozhi Fan

In this paper we study semi-parametric inference procedure for accelerated failure time models with auxiliary information about a main exposure variable. We use a kernel smoothing method to introduce the auxiliary covariate to the likelihood function. The regression parameters are then estimated through maximization of the estimated likelihood function. A consistent estimator of the variance of the estimator of the regression coefficients is proposed. Simulation studies show that the efficiency gain is remarkable when compared to just using the validation sample. The method is applied to the PBC data from the Mayo Clinic trial in primary biliary cirrhosis as an illustration.

PDF

Share this article

Google Scholar citation report
Citations: 3254

Journal of Biometrics & Biostatistics received 3254 citations as per Google Scholar report

Journal of Biometrics & Biostatistics peer review process verified at publons

Indexed In

 
arrow_upward arrow_upward