Daniel Nigusse Tollosa
Gent University, Belgium
Posters & Accepted Abstracts: J Cancer Sci Ther
Diet has been suggested to play a major role in the onset of colorectal cancer. To date, the validity of a comprehensive FFQ to assess risk factors for colorectal cancer had not been assessed in an elderly population. Hence, this study evaluated the ability of a self-administered semi-quantitative Food Frequency Questionnaire (FFQ) to measure consumption of foods and nutrients related to the development of colorectal cancer in a population >50 years old in Flanders, Belgium. The FFQ was administered during two days in a period of two weeks. The FFQ approach was validated by comparing to the 3-day diary method. Spearman correlations, Wilcoxon signed rant, Kappa tests and Bland-Altman plots were used to assess measurement agreement. 162 respondents (mean age 57.5 years, 59% female) provided data for the FFQ, of whom 156 also participated in the validity assessment. Correlation and classification agreement tests showed high reproducibility of the FFQ for measuring food and nutrient intake. For most of the foods and nutrients there was no significant difference between the first and second FFQ assessment in estimating foods and nutrients at a population level. Intake of ├ó┬?┬?fresh red meat├ó┬?┬?, ├ó┬?┬?total red meat├ó┬?┬?, ├ó┬?┬?total red meat plus meat products├ó┬?┬? and ├ó┬?┬?alcohol drinks├ó┬?┬? however, were significantly higher based on the FFQ compared to the 3-day diary method. For nutrients, Bland-Altman statistics revealed that only the mean difference in estimated alcohol intake differed substantially between both methods. For both the validity and reproducibility, measurement agreement at individual level varied widely at higher level of foods and nutrients intake. Therefore, the FFQ is a valid tool to estimate intake of foods and nutrients at a lower intake level to assess dietary exposure to colorectal cancer in an elderly population.
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