Title: A systematic review of therapeutical approaches in Biphosphonates-Related Osteonecrosis of the Jaw (BRONJ)

International Conference on Oral, Mouth and Throat Cancer

August 15-17, 2016 Portland, USA

Katia Rupel

University of Trieste, Italy

Posters & Accepted Abstracts: J Cancer Sci Ther

Abstract :

Objectives: The clinical management of Bisphosphonate-Related Osteo Necrosis of the Jaw (BRONJ) remains controversial. Since universally accepted guidelines haven�t been released yet, clinicians usually chose the type of treatment according to position papers based on expert opinion, or on empirical experience. The aim of this systematic review is to identify different therapeutical approaches for BRONJ that have been described in literature and to describe their effectiveness. Materials and Methods: A Medline via Pubmed and Scopus database literature search was conducted and all publications fulfilling the inclusion and exclusion criteria were included in eligibility assessment. The full texts of 146 retrieved articles were then screened and 40 studies were included in the quality assessment process. Results: After quality assessment, 22 full text articles were selected for the final review. 14 articles out of 22 were screened for stagerelated outcomes. The overall outcome results and results for every disease stage were the highest when patients were treated with extensive surgery or extensive laser assisted surgery.

Biography :

Email: m.biasotto@fmc.units.it