Synergistic antimicrobial and antifungal activity of Spondias mombin extracts and conventional antibiotic and antifungal agents on selected clinical micro organisms

International Conference on Medical and Clinical Microbiology

July 03-04, 2017 Bangkok, Thailand

Osuntokun Oludare Temitope, Ogunmodede A F, O A Fasusi, A O Thonda and A E Odufunwa

Adekunle Ajasin University, Nigeria
Obafemi Awolowo University, Nigeria

Posters & Accepted Abstracts: J Med Microb Diagn

Abstract :

Spondias mombim is a plant widely used in folkloric medicine. It has lots of potential as a medicinal plant. Most of these potentials are yet to be discovered. Its anti-infective property could be maximized either by using it alone or combining it with other plants and conventional antibiotics as a means of combating the problem of antibiotic resistance. The aim of the present work is to investigate the synergistic antimicrobial activity of various concentration of extracts of Spondias mombin and ofloxacin., investigate the synergistic antifungal activity of extract of Spondias mombin and fluconazole.Comparing the antimicrobial and antifungal activity of the various parts of the plant (leaf, bark and stem) and comparing the activity of the aqueous and crude ethyl acetate extracts of Spondias mombim.30 organisms were used for the research. They include 10 typed, 10 isolated bacteria and 10 fungal isolates. The results obtained revealed a higher zone of inhibition against the pathogens tested. The findings from this work suggest that Spondias mombim contain some compounds that can enhance the effect of conventional antibiotics and antifungal agents in inhibiting the growth of pathogens.

Biography :

Email: osuntokun4m@yahoo.com