Role of testicular cytology in evaluation of male infertility with special reference to ‘testicular mapping’

International Conference on Cytopathology

August 31-September 02, 2015 Toronto, Canada

Ravi Mehrotra

Institute of Cytology and Preventive Oncology, India

Posters-Accepted Abstracts: J Cytol Histol

Abstract :

Azoospermia is present in about 10-15% of men evaluated for infertility and represents the final result of different testicular alterations ranging from normal spermatogenesis with seminal tract obstruction or absence of vas deferens (obstructive azoospermia) to different problems of the spermatogenic process including hypospermatogenesis, maturation arrest and complete absence of germ cells (non obstructive azoospermia). Advances in assisted reproductive techniques (ART) have revolutionized the ability to help men with even the severest forms of male infertility to become fathers. Although finding sperms in men with obstructive azoospermia is not difficult, locating and retrieving spermatozoa in men with non-obstructive azoospermia remains a clinical challenge largely because sperm production in these men can be patchy or focal in nature. In response to this challenge, strategies such as fine-needle aspiration (FNA) mapping have been developed to find spermatozoa. The use of testicular FNA â�?�?mappingâ�? to systemically assess and localize sperm for ART in men with azoospermia and with testicular failure characterized by â�?�?patchyâ�? or â�?�?focalâ�? spermatogenesis is an innovative development in this field. A simple map (<4 sites/testis) is used to confirm the clinical expectation of sperm production in men who may be obstructed and azoospermic. On the other hand, compound map (>4 sites/testis) is typically performed as a diagnostic test to find sperm in failing testes. FNA mapping has gained considerable traction as an informative, â�?�?testis sparingâ�?�? technique for sperm detection in non-obstructive azoospermia performed on outpatient basis making it inexpensive, time-saving and painless procedure.

Biography :

Email: rm8509@gmail.com