Nizar Ahmed Al-Salahat
Stem Cell 4 Joints, Jordan
Posters & Accepted Abstracts: J Tissue Sci Eng
As we have seen, multiple studies related to the utilization of SVF for treating osteoarthritis for elderly patient who underwent various conservative treatments with no success, which showed encouraging results of regeneration of articular cartilage and meniscus. We have not seen any dedicated study for younger patients, active patients and elderly proactive patients that suffer from symptomatic advanced meniscus tear and/or loose bodies within the knee joint. These patients that have absolute indication for arthroscopy procedure usually undergo the standard partial or total meniscectomy procedure, this standard meniscectomy procedure have questionable outcomes and may increase the risk of early onset osteoarthritis as shown in various studies. The Pre-SVF arthroscopy concept is a technique that aim to treat the patients mechanical symptoms caused by symptomatic advanced meniscus tear and/or loose bodies (which is very doubtful that a solely intra-articular injection of SVF would solve these issues) and maintain the scaffold and the shape of the meniscus (which is not maintain in standard meniscectomy method). Therefore, the SVF injection following this technique of arthroscopy showed a higher regeneration rate of the meniscus, as well as the articular cartilage layer. The advantage of this Pre-SVF arthroscopy technique is to give patients a faster symptoms improvements and higher rate of regeneration of damaged tissue in the knee joint. Data showed significant improvements in pain and activity scales as well as meniscus and articular cartilage regeneration seen in posttreatment MRI images. This pilot study included 3 patients to be performed in large-scale and to be compared with solely SVF injection for similar indications.
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