Bellaje R1, Sefiani H1, 2, Ben Ali D1, Soulaymani A1 and Soulaymani Bencheikh R2,3
1University Ibn Tofail, Morocco 2Moroccan Poison Control and Drug Monitoring Center, Morocco 3University Mohammed V, Morocco
Scientific Tracks Abstracts: Pharmaceut Reg Affairs
Objectives: In Morocco the large number of cosmetic products is sold freely without control or registration. Some of these products can lead adverse reaction or poisoning in case of misuse or voluntary ingestion. The lack of knowledge of the composition of these products make therapeutic management in case of poisoning very difficult and sometimes causes unnecessary health spending even if these poisoning are often benign. The objective of this study is to establish the epidemiological profile of a poisoning by lightening creams collected at the Moroccan Poison Control and Pharmacovigilance center. Methods: This is a retrospective study of poisoning case by lightening creams collected at the Moroccan Poison Control and Pharmacovigilance Center between 1987 and 2011. Results: During the study period, 95 cases were collected. The mean age is 20 years├?┬▒1.4 [1-70 ans], and the F/M sex ratio is 1.73. In 90 (95%) cases, the route of poisoning was oral. The suicide attempts represent 33% of cases. Women are often voluntarily intoxicated. However, men were concerned by involuntary intoxication (p=0.003). Eighty three cases were urban (87%) and 90 cases occurred at home (95%). The digestive disorders were found in 68 cases associated or not with a neurological disorders (33 cases), cardiovascular disorders (14 cases), and respiratory distress (6 cases). The evolution was favorable in all cases. Conclusions: The implementation of the new law recording to the registration of cosmetic products in the ministry of health before marketing will ensure certainly a better orientation of the poisoning case management and improve the patient safety.
Bellaje R is Faculty of Sciences in Ibn Tofail University at Kenitra, Morocco.
Pharmaceutical Regulatory Affairs: Open Access received 471 citations as per Google Scholar report