Ovarian fibroma: A clinic-pathological study of 23 cases with review of literature

Cancer Science & Therapy

ISSN: 1948-5956

Open Access

Ovarian fibroma: A clinic-pathological study of 23 cases with review of literature

Experts Meeting on Gynecologic Oncology

May 19-21, 2016 San Antonio, USA

Nikhil S Parwate

Bramhakumaris Global Hospital and Research Centre, Mumbai

Posters & Accepted Abstracts: J Cancer Sci Ther

Abstract :

Purpose: The purpose of this study was to correlate the clinical findings, RMI-4 index, and frozen section in cases of ovarian fibroma with the final histopathology. Method: This is a retrospective study of clinical and pathological features of 23 patients of ovarian fibroma. The patient├ó┬?┬?s age ranged from 34 to 66 years (mean-49 years). The most common presenting symptom was abdominal pain. On clinical examination, the mean size of ovarian tumor was 9.5 cm, CA-125 levels were found to be raised in 14 patients and it was associated with ascites in 10 patients. USG showed a well circumscribed mass (with a mean size of 14 cm), on left side in 14 cases and on right side in 9 patients. RMI-4 was calculated in all the patients and it revealed the possibility of a benign histology in 17 patients. All patients underwent exploratory laparotomy with removal of ovarian tumor followed by frozen section examination. All but one (22/23) patient had positive correlation among frozen section and final histo-pathological findings. Results: Ovarian fibroma generally tends to occur in post-menopausal women. All the patients in our study of ovarian fibroma were symptomatic, with presence of palpable mass in majority of patients. RMI-4 Index co-related very well with benign nature of disease. Frozen section has an invaluable role at surgery; fertility conserving surgery is the choice in young women. Conclusion: Clinical findings, RMI-4 Index, frozen section, play a vital role before and at surgery in cases of benign ovarian tumors.

Biography :


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