Namrata Kafle
Padma Nursing College, Nepal
Posters & Accepted Abstracts: J Cardiovasc Dis Diagn
Introduction: Menopause is an inevitable physiological phenomenon in which cardiovascular risk factor
(CRF) factors association is reported, but age at menopause (AAM) varies considerably and could affect
the risk among post-menopausal women. The aim of the study was to clarify whether AAM is associated
with hypertension, independent of chronological age, lifestyle and hormone replacement therapy (HRT), in
Nepalese women.
Methods: A cross-sectional study was conducted using the baseline survey in 60 female among them 30
were post menopausal aged (45-55) study group and 30 pre menopausal aged (35-44) women considered to
be control group. The prevalence of hypertension in AAM groups was compared by using statistical analysis.
Daily lifestyle such as smoking, alcohol consumption, and doing brisk physical activity and women under
oral contraceptive pill were not included in this study.
Results: The estimated risk (odds ratio: OR) was significantly higher in post-menopausal women and linearly
elevated according to the AAM groups, and the late AAM group was more likely to have hypertension
however, after adjustment for age, BMI (kg/m(2)), HRT and lifestyle, AAM showed no significant
association with cardiovascular variables such as systolic, diastolic and pulse pressure when just considered
the menopausal status, therefore AAM group is not associated with increased risk of hypertension compared
with premenopausal control group attributed just because of menopausal status.
Conclusions: There is no any association of hypertension relevant to menopausal status confounding other
parameters such as age, BMI, life style and HRT therapy in the post-menopausal women.
Cardiovascular Diseases & Diagnosis received 427 citations as per Google Scholar report