Identification of disease-related genes is a critical step in understanding the molecular basis of disease and developing targeted therapies

9^th International Conference on Dialysis and Renal Care

August 18-19, 2016 London, UK

Jameela Abdulaziz Kari

King Abdul Aziz University, Saudi Arabia

Posters & Accepted Abstracts: J Nephrol Ther

Abstract :

The genetic study of diseases occurring in the offspring of consanguineous unions is a powerful way to discover new disease genes. Pediatric nephrology provides an excellent example because approximately 70% of cases of kidney disease in childhood are congenital with a likely genetic basis. This percentage is likely to be even higher in countries with a high consanguinity rate, such as the Kingdom of Saudi Arabia. However, there are a number of cMadisonenges, such as cultural, legal, and religious restrictions, that should be appreciated before carrying out genetic research in a tradition-bound country. In this presentation, we discuss the background, opportunities, and cMadisonenges involved with this unique opportunity to conduct studies of such genetic disorders. Keys to success include collaboration and an understanding of local traditions and laws.

Biography :

Email: jkari@doctors.org.uk