Evaluation of coelomic fluids and its clinical correlation with cytological diagnosis

International Conference on Cytopathology

August 31-September 02, 2015 Toronto, Canada

Anita Bhandari

Chitwan Medical College, Nepal

Posters-Accepted Abstracts: J Cytol Histol

Abstract :

Coelomic fluid aspiration is a simple technique to achieve a diagnosis which helps in narrowing the diagnostic dilemma faced by physicians. This was a prospective study conducted during January 2012 to May 2013 in the department of pathology, CMSTH, Bharatpur, Nepal. Out of 70 cases, 34 cases are of peritoneal fluid, 31 cases are of pleural fluid and five cases are of pericardial fluid. 59 cases diagnosed as chronic effusion (84.28%). Six cases are diagnosed as inflammatory effusion (8.57%) and five cases are of malignant effusion (7.14%). Out of 70 cases, 50% were turbid, 47% were clear and 2.9% were hemorrhagic. 52.9% of effusions were exudative and 47.1% of effusion was transudative. Mean glucose level of transudative effusion was 80.15�±21.19 mg/dl which was higher compared to exudative effusion. Mean proteins levels in transudative effusion was 2.08�±0.43 gm/dl. The total leukocyte count ranged from 57 to 1, 50,000 cells/mm3. The estimated Mean�±SD of all coelomic fluid cell count was 3151.5�±17974.06 with average cell counts in malignant, chronic and inflammatory effusion of 620 cells/mm3, 520 cells/mm3 and 31,141 cells/mm3 respectively. The estimated Mean�±SD of all transudative fluid total leukocyte count was 188.57�±53.65 and of exudative fluid cell count was 5793.29�±24576.28. Overall sensitivity of cytology was 60%, specificity 96.92% and accuracy 94.28% while positive predictive value was 60% and negative predictive value was 96.92%. Hence, cytological study of the fluid is a complete diagnostic modality which aims at pointing out the etiology of effusion as well as in certain cases a means of prognostication of disease process.

Biography :

Email: dranitabagale@gmail.com