Diversity and evolution of the developmental transcriptome in flowering plants

9^th International Conference on Genomics & Pharmacogenomics

June 15-16, 2017 London, UK

Christoph Schuster, Alexander Gabel, Hajk-Georg Drost, Ottoline Leyser, Ivo Grosse and Elliot M Meyerowitz

University of Cambridge, UK
Martin-Luther-Universit�¤t Halle-Wittenberg, Germany
German Centre for Integrative Biodiversity Research (iDiv), Germany
Howard Hughes Medical Institute, USA
California Institute of Technology, USA

Posters & Accepted Abstracts: J Mol Genet Med

Abstract :

The development of higher plants requires an exquisite spatio-temporal regulation of their transcriptomes. Although organ and cell type-specific analyses of global gene expression patterns in the model plant Arabidopsis thaliana were performed a decade ago, the dynamic nature of the non-coding transcriptome is poorly understood. Using strand-specific total RNA-Seq, we have investigated the expression patterns of natural antisense transcripts (NATs), long-intergenic RNAs (linc RNAs) and other non-coding transcripts, as well as the tissue-specific usage of isoforms throughout Arabidopsis development. The evidence for an in vivo function has only been shown for a small fraction of long non-coding RNAs and splice variants in plants to date, we use a comparative approach to predict functional importance. By dissecting the developmental transcriptomes of seven plant species, we will be able to identify the conserved elements and provide insight into the evolutionary history of long non-coding RNA expression and differential exon usage patterns in flowering plants.

Biography :

Email: christoph.schuster@slcu.cam.ac.uk