Determinants of cardiac ejection fraction for the patients with Dobutamine Stress Echocardiography

JOINT EVENT ON 2^nd International Conference on Hypertension & Healthcare and 2^nd International Conference on Non-invasive Cardiac Imaging, Nuclear Cardiology & Echocardiography

September 11-13, 2017 | Amsterdam, Netherlands

Rabindra Nath Das

The University of Burdwan, India

Posters & Accepted Abstracts: J Hypertens

Abstract :

Objectives: This article aims to identify the determinants of the baseline cardiac ejection fraction, and the ejection fraction on Dobutamine dose of 558 heart patients who underwent Dobutamine stress echocardiography (DSE). Background: There is less information known about the determinants of ejection fraction with DSE. Methods: The response ejection fraction is positive, heterogeneous, and gamma distributed, so joint generalized linear gamma models fitting is used. Results: The baseline cardiac ejection fraction (baseEF) increases with the increased of peak heart rate (pkhr) (P=0.0247), systolic blood pressure (sbp) (P=0.0007), ejection faction on Dobutamine (dobEF) (P<0.001). The baseEF decreases with the increased of double product (DP) of peak heart rate & systolic blood pressure (sbp) (P=0.0017) and Dobutamine dose given (dose) (P=0.0255). The baseEF increases of the cardiac patients who underwent DSE having recent angioplasty (newPTCA) (P=0.0101), history of myocardial infraction (hxofMI) (P=0.0658), and baseline electrocardiogram diagnosis (ECG) at normal level (P=0.0555). The baseEF increases of the cardiac patients with DSE not having resting wall motion abnormality on echocardiogram (ECDG) (restwma) (P=0.0003), positive stress echocardiogram (posSE) (P<0.001), history of PTCA (hxofPTCA) (P=0.0384). On the other hand, the ejection fraction on Dobutamine dose (dobEF) increases with the increased of (DP) (P=0.0007), (dose) (P=0.0110), (baseEF) (P < 0.001), and it decreases with the increased of (sbp) (P=0.0012). The dobEF increases of the cardiac patients with DSE having (posSE) (P<0.001), new myocardial infraction (new MI) (P=0.0054), recent bypass surgery (new CABG) (P=0.0049), and it increases of the cardiac patients with DSE not having (new PTCA). In addition, the dobEF decreases of the cardiac patients with DSE having heavy history of smoking (hxofCig) (P=0.0261). Conclusions: Impacts of pkhr, basal blood pressure, sbp, mbp, Dobutamine dose, heart conditions, heavy smoking and others on baseEF and dobEF have been identified based on probabilistic Modelling. Most of the present findings and their effects are almost new in the cardiac ejection fraction diagnosis literature.