Enxiang Zhou, Lun Li, Liqin Yuan, Xianyu Chen, Quan Wang, Jinhui Tian and Kehu Yang
The Second Xiangya Hospital-Central South University, China
Xijing Hospital-Fourth Military Medical University, China
Lanzhou University, China
Posters & Accepted Abstracts: J Cancer Sci Ther
Background & Objective: Breast cancer-related lymphedema (BCRL) is a disabling complication with long term impact on quality on life after breast cancer treatment. Management of BCRL remains a major challenge for patients and health care professionals. The goal of this overview is to summarize the effects of different treatment strategies for patients with BCRL. Methods: A thorough search was undertaken to include SR or meta-analysis about the treatments for BCRL. Two investigators independently selected studies and abstracted the data. Results: Combined physical therapy (CPT) and different combinations of its constituent, surgery, oral pharmaceuticals, low-level laser therapy, weight reduction, mesenchymal stem cells therapy, Kinesio Tex taping, and acupuncture might be effective in reducing lymphedema, except exercise. The results of direct comparisons showed CPT might be more effective than standard physiotherapy (ST). Manual lymphatic drainage (MLD) may not offer additional benefit to ST for swelling reduction, but to compression bandaging. MLD seemed to have similar effects on self-administered simple lymphatic drainage (SLD) or intermittent pneumatic compression pump (IPC). IPC might also not be associated addition effectiveness to CPT. The effects of stem cell therapy vs. compression sleeve or CPT, as well as the effects of Daflon and coumarin were not established. Conclusion: Although lots of treatments on BCRL might reduce lymphedema volume, their effects were not well established. The quality of original studies in included reviews were poor, future RCTs should be well conducted and reported.
Cancer Science & Therapy received 3644 citations as per Google Scholar report