Analysis of parabens in protein based food supplements

International Conference on Pharmaceutical Chemistry

September 05-07, 2016 Frankfurt, Germany

Ulviye Acar Cevik, Serkan Levent and Yusuf Ozkay

Anadolu University, Turkey

Posters & Accepted Abstracts: Med chem

Abstract :

Parabens have been employed for about a century as preservatives in foodstuff, cosmetics and pharmaceuticals, beverage.In vitro studies indicate that PBs induce the growth of MCF-7 human breast cancer cells and influence the expression of estrogen dependent genes. In this respect and although parabens were generally considered harmless to human beings for a long time, several concerns have been raised over the past twenty years about parabens safety with emphasis given on their endocrine disrupting potential.The protein-containing food supplements within the over the counter (OTC) drug class content has been scanned through its content and a paraben analysis of the supplement was performed. In the study, 2 pieces of energizing gel, 9 pieces of protein or amino acid-containing supplement, and 7 pieces of supplements containing L-carnitine which totals to 18 products have been purchased from 16 different companies. In the analysis, the LCMS-IT-TOF device has been used. The peaks which were observed in a High-Resolution Mass spectrum has been scanned within a range of 10 ppm molecular mass from the drugbankdatabase and eventually, a qualitative analysis of related compounds were performed. As a result of the analysis, no parabens were detected in any products. However, in those products, which are used by a wide range of age group, was noted to have a high level of carbohydrate content (especially fructose and sucrose).

Biography :

Ulviye Acar Çevik has graduated with his Master’s degree in 2015. Currently, she is pursuing PhD and is in the second semester of PhD.

Email: uacar@anadolu.edu.tr