An atypical case of viral thyroiditis culminating into Graves thyrotoxicosis

Joint Event on 3^rd International Conference on ENDOCRINOLOGY AND METABOLIC SYNDROME & 12^th International Conference on ABDOMINAL IMAGING AND ENDOSCOPY

June 28-29, 2018 Amsterdam, Netherlands

Ashutosh Kapoor

Queen Elizabeth Hospital, Gateshead, UK

Posters & Accepted Abstracts: J Metabolic Synd

Abstract :

Statement of the Problem: Grave’s disease is an autoimmune condition, characterized by features of hyperthyroidism, such as palpitations, sweating, disturbed sleep pattern, anxiety and atrial fibrillation, to name a few. This disease displays a strong link to both hereditary inheritance and smoking, amongst other factors. The abnormal immune response is characterized by the presence of antibodies directed against thyroid tissue antigens, including antibodies that react with the thyrotrophin receptor by binding to the receptor. Subacute/viral thyroiditis is a form of thyroiditis that can be a causative factor for both hyper/hypothyroidism. The most common form of this condition is De Quervain’s thyroiditis, which manifests as a painful enlargement of thyroid gland accompanied by fever and a sore throat. Methodology & Theoretical Orientation: Information for the case was compiled via GP records, online ICE reporting system, discharge letters and clinic attendance letters on MEDWAY software. Further information was sought out from the endocrinology team based at QEH, Gateshead. Findings: In summary, this was a case with a learning curve from the endocrine point of view, for two main reasons; one the fact that, this gentleman initially presented with evidence of viral thyroiditis, with TRAB antibodies-negative, following which the inflammatory nature of subacute/viral thyroiditis may have led to the activation of an autoimmune response in susceptible subjects, resulting in the onset of Grave’s disease. Conclusion & Significance: The cause of Grave’s disease following subacute thyroiditis is still not known. It is believed however, that the inflammatory nature of subacute thyroiditis, may lead to the activation of the autoimmune response, thus leading to the development of Grave’s disease

Biography :

E-mail: ashu.kap89@gmail.com