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Scholarly Open Access Heart Journal | Open Access Journals
Cardiovascular Diseases & Diagnosis

Cardiovascular Diseases & Diagnosis

ISSN: 2329-9517

Open Access

Scholarly Open Access Heart Journal

Takotsubo cardiomyopathy is an important differential consideration when a patient presents with an acute coronary syndrome. Patients typically present with chest pain/pressure, shortness of breath, electrocardiographic changes, elevated biomarkers, normal or near normal coronary arteries, and wall motion abnormalities that are not consistent with a single coronary vascular bed. This constellation of findings is often associated with a precipitating emotional or physical stressor.

Variants of the classic left ventricular apical ballooning syndrome, including mid- and basal left ventricular wall motion abnormalities, are being more frequently recognized. The recognition and diagnosis of takotsubo cardiomyopathy has important implications for clinical management initially and in follow up. A small subset of patients may experience life-threatening complication during initial presentation, however, most patient recover and have a favorable long-term prognosis. The pathophysiology of takotsubo cardiomyopathy remains an enigma, but a surfeit of catecholamines seems pertinent to the underlying pathophysiology.

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Citations: 427

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