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Metabolomics:Open Access

Metabolomics:Open Access

ISSN: 2153-0769

Open Access
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Scholarly Open Access Glycomics Journals

 

 

A large variety of glycans is intricately located on the cell surface, and the overall profile (the glycogen, given the entire repertoire of glycoconjugate-associated sugars in cells and tissues) is believed to be crucial for the diverse roles of glycan’s, which are mediated by specific interactions that control cell-cell adhesion, immune response, microbial pathogenesis, and other cellular events. The glycaemic profile also reflects cellular alterations, such as development, differentiation, and cancerous change. A glycoconjugate-based approach would, therefore, be expected to streamline the discovery of novel cellular biomarkers. Development of such an approach has proven challenging, due to the technical difficulties associated with the analysis of various types of cellular glycan’s; however, recent progress in the development of analytical methodologies and strategies has begun to clarify the cellular glycaemic of various classes of glycoconjugates. This review focuses on recent advances in the technical aspects of cellular glycomic analyses of major classes of glycoconjugates, including N- and O-linked glycans, derived from glycoproteins, proteoglycans, and glycosphingolipids. Articles that unveil the glycaemic of various biologically important cells, including embryonic and somatic stem cells, induced pluripotent stem (iPS) cells

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Citations: 895

Metabolomics:Open Access received 895 citations as per Google Scholar report

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