Research testament is available that habitual sodium (as salt, NaCl) intake is related directly to blood pressure (BP).1 For example, in the INTERSALT (International Cooperative Study on Salt, Other Factors, And Blood Pressure) involving 10 079 women and men 20 to 59 years of age from 52 population samples in 32 countries, ecological (cross-population) analyses (n=52) showed significant independent relations between sample 24-hour median sodium (Na) excretion and sample median BP (systolic BP [SBP] and diastolic [DBP]), and prevalence of high BP. INTERSALT within-community analyses on entity (n=10 079) showed a significant positive independent linear relation between 24-hour urinary Na excretion and SBP. However, disagreements continue to prevail as to the importance of dietary salt In the INTERMAP (International Study on Macro/Micronutrients and Blood Pressure) of 4680 women and men 40 to 59 years of age from 17 population samples in Japan, People’s Republic of China, United Kingdom, and United States, each participant collected 2 timed 24-hour urine samples. Analyses here use these INTERMAP data to assess the quantitative relation to BP of 24-hour urinary Na excretion and the urinary sodium to potassium (Na/K) ratio, and to evaluate whether utilization of multiple macro/micronutrients modulated these Na–BP relations.
Research Article: Journal of Hypertension: Open Access
Research Article: Journal of Hypertension: Open Access
Research Article: Journal of Hypertension: Open Access
Research Article: Journal of Hypertension: Open Access
Research Article: Journal of Hypertension: Open Access
Research Article: Journal of Hypertension: Open Access
Research Article: Journal of Hypertension: Open Access
Research Article: Journal of Hypertension: Open Access
Research Article: Journal of Hypertension: Open Access
Research Article: Journal of Hypertension: Open Access
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Journal of Hypertension: Open Access received 614 citations as per Google Scholar report