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RNA Interference | Open Access Journals
Journal of Genetics and DNA Research

Journal of Genetics and DNA Research

ISSN: 2684-6039

Open Access

RNA Interference

RNA interference (RNAi) is a biological process in which RNA molecules inhibit gene expression or translation, by neutralizing the targeted mRNA molecules. . A detailed study of each of these seemingly different processes has elucidated that the identity of these phenomena is in fact RNAi. Andrew Fire and Craig C. Mello shared the 2006 Nobel Prize in Physiology or Medicine for their work on RNA interference in the nematode worm Caenorhabditis elegans, which they published in 1998. Since the discovery of RNAi and its regulatory potentials, it has become evident that RNAi has immense potential in the suppression of desired genes. RNAi is now known as a precise, efficient, stable and better technology than antisense for the suppression of genes. However, antisense RNA produced intracellularly by an expression vector can be developed and find utility as new therapeutic agents.

 

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