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Review Articles On Ichthyosis Vulgaris | Open Access Journals
Alternative & Integrative Medicine

Alternative & Integrative Medicine

ISSN: 2327-5162

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Review Articles On Ichthyosis Vulgaris

Ichthyosis vulgaris (IV) is an inherited skin condition characterized by an accumulation of cells in the stratum corneum that manifests itself in xerotic scales in the form of plaques. It is more important on the extensor surfaces of the extremities, back, abdomen and legs and presents a palmar hyperlinearity (Takeichi and Akiyama, 2016). If not properly treated, this buildup can lead to difficulties in patient care and a reduced quality of life for people with this condition.

There are more than 20 types of ichthyosis that include epidermolytic ichthyosis, congential reticular ichthyosiform erythroderma, and lamellar ichthyosis, with IV being the most common type of hereditary non-syndromic ichthyosis characterized by reduced granules keratohyaline or an absence of a grainy layer (Takeichi, 2016). This IV is caused by mutations in the filaggrin gene (FLG) associated with this skin barrier formation and has variable phenotypic manifestations. IV is strongly associated with other atopic skin manifestations such as atopic dermatitis and seborrheic dermatitis. Features of IV include visible flaking and dryness which spares flexing surfaces, hyperlinearity of the palm and sole, and a strong disposition for comorbidities of allergic diseases such as asthma and seasonal allergies

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