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Pseudomonas Aeruginosa | Open Access Journals
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Journal of Microbiology and Pathology

ISSN: 2952-8119

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Pseudomonas Aeruginosa

Pseudomonas aeruginosa is a rod-shaped, rod-shaped, gram-negative, monoflagellated bacterium. It has a pearly appearance and a grape or omelette smell. P. aeruginosa grows well at a temperature of 25 ° C to 37 ° C, and its ability to grow at 42 ° C helps distinguish it from many other Pseudomonas species. P. aeruginosa is a ubiquitous microorganism that has the ability to survive under a variety of environmental conditions. It not only causes diseases in plants and animals, but also in humans, causing severe infections in immunocompromised cancer patients and patients suffering from severe burns and cystic fibrosis (CF). Most P. aeruginosa strains produce one or more pigments, including pyocyanin (blue-green), pyoverine (yellow-green and fluorescent), and pyorubin (red-brown). Previous research has suggested that pyocyanin not only contributes to the persistence of P. aeruginosa in the lungs of CF patients, but also interferes with many functions of mammalian cells, including cellular respiration, ciliary beat, growth epidermal cell, calcium homeostasis and prostacyclin release from lung endothelial cells [1]. However, the precise molecular mechanism mediated by pyocyanin pathology is unknown.

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