Proteoglycans and their glycosaminoglycans (GAGs) are fundamental forever on the grounds that they are answerable for the organization of numerous basic capacities in tissue improvement and homeostasis, including biophysical properties and jobs in cell flagging and gathering. of the extracellular grid. So as to catch these organic capacities, a scope of biomaterials is intended to fuse standard GAGs, by and large secluded from creature sources, for tissue designing, sedate conveyance and regenerative medication applications. All GAGs, aside from hyaluronan, are available in the body covalently coupled to the protein core of proteoglycans, however the joining of proteoglycans into biomaterials remains moderately unexplored. Proteoglycan-based biomaterials are more likely to summarize tissue-specific GAG profiles and the native presentation of GAGs in human tissue. The protein core gives extra organic usefulness, including cell authoritative, development factor and extracellular network areas, just as destinations for protein immobilization sciences. Finally, proteoglycans can be expressed recombinantly in mammalian cells and thus offer possibilities for genetic manipulation and metabolic engineering to control the structures and functions of proteins and GAGs. This progress report summarizes current developments in GAG-based biomaterials and presents emerging research and future opportunities for the development of biomaterials that incorporate GAGs presented in their native proteoglycan form.
Keynote: Journal of AIDS & Clinical Research
Keynote: Journal of AIDS & Clinical Research
Posters & Accepted Abstracts: Journal of Advanced Practices in Nursing
Posters & Accepted Abstracts: Journal of Advanced Practices in Nursing
Posters & Accepted Abstracts: Journal of Advanced Practices in Nursing
Posters & Accepted Abstracts: Journal of Advanced Practices in Nursing
Scientific Tracks Abstracts: Journal of Advanced Practices in Nursing
Scientific Tracks Abstracts: Journal of Advanced Practices in Nursing
Posters & Accepted Abstracts: Journal of Advanced Practices in Nursing
Posters & Accepted Abstracts: Journal of Advanced Practices in Nursing
Clinical and Medical Case Reports received 53 citations as per Google Scholar report