Shariq Ahmad Wani*, Mohammed Sharfraz Ahamed, Shruthi Jayaram, and Shariq R. Masoodi
Sodium glucose co-transporter-2 inhibitors are associated with a range of adverse effects including Diabetic ketoacidosis both euglycemic and Hyperglycemic. However, this case report highlights a rare case of DKA/HHS overlap in a patient who was treated with SGLT2i. Most patients recover with prompt recognition and treatment, patient education about identifying early signs remains a cornerstone of early identification and treatment.
Jullia Greque Calabrez*, Victoria Caroline Danielli da Silva, Antônio Chambo Filho, Coridon Franco da Costa, Mariana Kuster de Freitas, Extefana Pereira Souza and Diego Pillo Sueth
Introduction: Arteriovenous Malformation (AVM) is a rare vascular abnormality characterized by a direct connection between arteries and veins without an intervening capillary network, resulting in increased circulatory volume and a risk of severe complications. In the gynecological context, uterine AVM is uncommon but clinically significant due to its association with severe and difficult-to-control hemorrhage. Objective: To describe the case of a primiparous patient who was diagnosed with a uterine arteriovenous malformation following cesarean delivery, highlighting the clinical findings and the management approach adopted during follow-up. Methods: This descriptive study was conducted as a clinical case report, based on a retrospective analysis of clinical, laboratory, and imaging data from a patient diagnosed with AVM. Data were collected through a systematic review of the electronic medical records of Hospital Santa Casa de Misericórdia de Vitória (HSCMV), ensuring compliance with ethical principles and data confidentiality. Expected results: This case report is expected to contribute to the expansion of knowledge regarding uterine AVM. The findings are anticipated to emphasize the importance of early diagnosis, even in cases with nonspecific clinical manifestations, as well as to highlight the challenges associated with therapeutic management. Consequently, this report aims to raise awareness among healthcare professionals regarding subtle clinical signs of the condition and to promote more accurate and appropriate clinical decision-making in relevant settings.
Lyvia do Prado Pacheco*, Amanda Borges, Gabriela Heringer, Lícia Gobeti, Luciene Lage da Motta and Antônio Chambô Filho
DOI: 10.37421/2684-4915.2026.10.413
Background: Primary fallopian tube cancer is a rare and highly malignant neoplasm, frequently confused with ovarian cancer. Among the risk factors, mutations in the BRCA-1 and BRCA-2 genes play an important role. The gold standard for diagnosis is postoperative histological examination. Treatment is based on surgery, and patients with BRCA-½ mutations are indicated for screening and preventive rehabilitation due to the high risk of tumor of the fallopian tube. This article aims to report the case of a 58-year-old patient with a condition of a solid serous carcinoma of the fallopian tube.
Methods: The information was obtained through analysis and review from the patient's medical record, photographic records of the lesions, and literature review.
Results: It is demonstrated that a significant number of serous carcinomas pelvic are originated in the fallopian tubes, especially in patients carrying mutations in the BRCA1 genes and BRCA2. In this reported case, the absence of ovarian abnormalities and the isolated involvement of the fallopian tube support this interpretation; moreover, the presence of a BRCA1 mutation reinforces the increased risk and the need for risk-reducing salpingo-oophorectomy. Even in the early stages, it is noticeable that high-grade serous neoplasms present a high risk of recurrence, and adjuvant chemotherapy is indicated based on staging, tumor grade, and genetic profile.
Conclusion: The reported case reinforces the importance of evaluating and considering the fallopian tube as a site of origin for serous carcinomas, particularly in patients with BRCA1 or BRCA2 mutations. The association between genetic factors and the tumor’s morphological characteristics highlights the relevance of follow-up and individualized prevention strategies in these patients.
Clinical and Medical Case Reports received 53 citations as per Google Scholar report
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