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Neuronal Marker Journals | Open Access Journals
Hepatology and Pancreatic Science

Hepatology and Pancreatic Science

ISSN: 2573-4563

Open Access

Neuronal Marker Journals

Obesity has grown to epidemic proportion throughout the world. Its complications include diabetes, cardiovascular diseases and chronic diseases. However the exact pathophysiology of obesity is still unclear. Excessive food intake seems to play a role in the development of obesity. Role of hypothalamus in the control of food intake has been well-documented. However, human studies on eating behaviors indicated that hypothalamus may receive input from other brain regions, particularly from cortex. Using positron emission tomography  scan, we investigated brain responses to the meal stimulations in certain population such as lean, obese subjects, and lean people who has history of severe obese but successfully maintained weight loss . Results in lean individuals indicated that satiety was associated with increases rCBF in the left dorso-lateral prefrontal cortex .

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