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Myocardial Ischemia Scholarly Journal | Open Access Journals
Journal of Morphology and Anatomy

Journal of Morphology and Anatomy

ISSN: 2684-4265

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Myocardial Ischemia Scholarly Journal

The myocardium, similar to most other muscle, parade a relation between velocity of contraction and the pre-contraction tension. The increased velocity, as with any increase in energy, requires an increase in oxygen consumption. Within the myocardium the pre-contraction tension (myocardial wall tension) has a sunny relation with the pre-contraction ventricular volume, where even relatively small changes in volume will be associated with quite large changes in wall tension. This too is an important therapeutic parameter to consider. Nitrate drugs, protracted considered to exert their action via epicardial coronary vasodilatation, now appear to exert their ramification by modulation of myocardial wall tension. Nitrates are profound venodilators that reduce the venous restoration to the heart and thus reduce left ventricular volume, reducing myocardial wall tension and thus reducing MV̇O2 at all levels of myocardial work. It is for this reason that patients often associate the onset of their headache succeeding nitrate administration (due to venous distension) with the deffervescence of their angina attack.

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Citations: 63

Journal of Morphology and Anatomy received 63 citations as per Google Scholar report

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