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Mucins In Gastric Cancer | Open Access Journals
Journal of Cancer Clinical Trials

Journal of Cancer Clinical Trials

ISSN: 2577-0535

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Mucins In Gastric Cancer

Gastric cancer it is one of the most ordinary and hostile cancer types throughout the world. Most Gastric Cancer associates with dysfunction of the mucosal barrier in the stomach, the first line of defence against pathogens and inflammation. Impairment of the gastric mucosal barrier often leads to chronic inflammation, a major contributor to the development of Gastric Cancer. One of the main components of the mucosal barrier that protects the underlying stomach epithelium is the mucin family of high molecular-weight glycosylated proteins [3, 4], with 21 mucin genes identified (MUC1-MUC21) so far. In recent years, mucins have also been found to be both therapeutic targets and biomarkers predicting the prognosis of various cancers

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