Medullary Carcinomas

Medullary carcinoma is a tumor of C cells, which normally produce calcitonin. Medullary carcinoma is a typical neuroendocrine tumor with a finely divided nuclear chromatin which may show nuclear molding . A wide variety of morphological variants of spinal cord carcinoma have been described, and some tumors are associated with an amyloid stroma. Many spinal cord carcinomas occur in type I multiple endocrine neoplasia (MEN). These patients have germline mutations in the MEN gene, and tumors tend to appear in diffuse C-cell hyperplasia , which can be demonstrated immunohistochemically by staining for calcitonin. Medullary carcinomas can metastasize relatively early in their course. Calcitonin is a useful cellular and serum biomarker for these neoplasms and can be used to assess residual and recurrent diseases.

High Impact List of Articles

Tumor Budding as a Useful Prognostic Indicator in Early Oral Squamous Cell Carcinoma
Tadaaki Kirita, Nobuhiro Yamakawa, Nobuhiro Ueda and Takahiro Yagyuu
Review Article: Cancer Science & Therapy
Tumor Budding as a Useful Prognostic Indicator in Early Oral Squamous Cell Carcinoma
Tadaaki Kirita, Nobuhiro Yamakawa, Nobuhiro Ueda and Takahiro Yagyuu
Review Article: Cancer Science & Therapy
Imaging Features, Differential Diagnosis and Management of Leiomyosarcomas: Case Series and Review of the Literature
Stramare R, Orsatti G, Attar S, Rastrelli M, Brunello A, Bortolanza C, Ortolan P and Coran A
Research Article: Cancer Science & Therapy
Imaging Features, Differential Diagnosis and Management of Leiomyosarcomas: Case Series and Review of the Literature
Stramare R, Orsatti G, Attar S, Rastrelli M, Brunello A, Bortolanza C, Ortolan P and Coran A
Research Article: Cancer Science & Therapy
Comparative Analysis of Dose Variations in Tumor Volumes and Organs at Risk in IMRT Plans for Head-AndÃƒÂ¢Ã‚â‚¬Ã‚â€œNeck, Pelvis and Brain Cancers with Varying Dose Calculation Grid Sizes
Pathak P, Guha S, Vitwekar Vidya, Majumder Sourav and Soni Ashok
Research Article: Cancer Science & Therapy
Comparative Analysis of Dose Variations in Tumor Volumes and Organs at Risk in IMRT Plans for Head-AndÃƒÂ¢Ã‚â‚¬Ã‚â€œNeck, Pelvis and Brain Cancers with Varying Dose Calculation Grid Sizes
Pathak P, Guha S, Vitwekar Vidya, Majumder Sourav and Soni Ashok
Research Article: Cancer Science & Therapy
Landmark Studies in Radiation Oncology: Has the Pattern of Publication Changed?
Carsten Nieder, Hans Geinitz, Nicolaus H Andratschke and Anca L Grosu
Research Article: Cancer Science & Therapy
Landmark Studies in Radiation Oncology: Has the Pattern of Publication Changed?
Carsten Nieder, Hans Geinitz, Nicolaus H Andratschke and Anca L Grosu
Research Article: Cancer Science & Therapy
Effect of Y-90 SIR-Spheres Therapy for Multiple Liver Metastases in a Variety of Tumors
Isis W. Gayed, Hisham Wahba, David Wan, Usha Joseph and Ravi Murthy
Research Article: Cancer Science & Therapy
Effect of Y-90 SIR-Spheres Therapy for Multiple Liver Metastases in a Variety of Tumors
Isis W. Gayed, Hisham Wahba, David Wan, Usha Joseph and Ravi Murthy
Research Article: Cancer Science & Therapy

Conference Proceedings

Tumoral expression of pyruvate kinase L/R as a predictive marker for treatment of metastatic renal cancer patients with sunitinib and sorafenib
Marjut Niinivirta,Gunilla Enblad, Cecilia Lindskog,Fredrik Ponten, Anca Dragomir and Gustav Ullenhag
Scientific Tracks Abstracts: Cancer Science & Therapy
Tumoral expression of pyruvate kinase L/R as a predictive marker for treatment of metastatic renal cancer patients with sunitinib and sorafenib
Marjut Niinivirta,Gunilla Enblad, Cecilia Lindskog,Fredrik Ponten, Anca Dragomir and Gustav Ullenhag
Scientific Tracks Abstracts: Cancer Science & Therapy
The mechanism & causes of carcinogenesis and mutagenesis in eukaryotes
Shaukat Iqbal Malik
Posters & Accepted Abstracts: Cancer Science & Therapy
The mechanism & causes of carcinogenesis and mutagenesis in eukaryotes
Shaukat Iqbal Malik
Posters & Accepted Abstracts: Cancer Science & Therapy
Micelle-encapsulated thiostrepton is an effective nanomedicine for inhibiting tumor growth
Andrei L. Gartel
Accepted Abstracts: Cancer Science & Therapy
Micelle-encapsulated thiostrepton is an effective nanomedicine for inhibiting tumor growth
Andrei L. Gartel
Accepted Abstracts: Cancer Science & Therapy
The low-molecular-weight compound MS-444 selectively targets cancer cells via inhibition of the mRNA stability factor HuR
Fernando F. Blanco, Nicole-Claudia Meisner and Dan A. Dixon1s
Posters: Cancer Science & Therapy
The low-molecular-weight compound MS-444 selectively targets cancer cells via inhibition of the mRNA stability factor HuR
Fernando F. Blanco, Nicole-Claudia Meisner and Dan A. Dixon1s
Posters: Cancer Science & Therapy
New generation health care delivery through smart labs capable of offering next-generation sequencing based multi-gene panels
Harsha K Rajasimha
ScientificTracks Abstracts-Workshop: Journal of Health & Medical Informatics
New generation health care delivery through smart labs capable of offering next-generation sequencing based multi-gene panels
Harsha K Rajasimha
ScientificTracks Abstracts-Workshop: Journal of Health & Medical Informatics

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Cancer Science & Therapy