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Kawasaki Disease | Open Access Journals
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Journal of Infectious Diseases and Medicine

ISSN: 2576-1420

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Kawasaki Disease

Kawasaki disease is an acute, self-limited vasculitis of unknown etiology that happens predominantly in infants and youngsters . If not treated in an initial stage with a high-dose intravenous immunoglobulin, 1 in 5 children can develop coronary artery aneurysms; this risk is reduced 5-fold if an intravenous immunoglobulin could run within 10 days of fever onset. Coronary artery aneurysms evolve dynamically over time, usually reaching a high dimension by 6 weeks after illness onset. Almost all the morbidity and mortality occur in patients with giant aneurysms. Risk of myocardial infarct from arteria coronaria thrombosis is greatest within the first 2 years after illness onset. However, stenosis and occlusion progress over years. Indeed, Kawasaki disease is not any longer a rare explanation for acute coronary syndrome presenting in young adults. Both coronary artery bypass surgery and the percutaneous intervention were used to treat Kawasaki disease patients whom ever  developed with myocardial ischemia as a consequence of coronary artery aneurysms and stenosis.

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