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HIV Drug Resistance | Open Access Journals
Journal of AIDS & Clinical Research

Journal of AIDS & Clinical Research

ISSN: 2155-6113

Open Access

HIV Drug Resistance

Once a person is infected with HIV, the virus begins to multiply in the body. As HIV multiplies, it sometimes changes shape (mutates). Some HIV mutations that develop while a person is taking HIV drugs can lead to drug-resistant HIV.

 

Once drug resistance develops, the anti-HIV drugs that previously controlled the person's HIV are no longer effective. In other words, anti-HIV drugs cannot stop drug-resistant HIV from multiplying. Drug resistance can cause anti-HIV treatment to fail.

 

Drug-resistant HIV can spread from person to person  is known as transmitted resistance. People with transmitted resistance have HIV resistant to one or more anti-HIV drugs before they even start taking anti-HIV drugs.

 

Once HIV treatment has started, a viral load test is used to check whether anti-HIV drugs are controlling a person's HIV. If the viral load test indicates that a person's HIV regimen is not working, the drug resistance test is repeated. Test results can identify if drug resistance is the problem and, if so, can be used to select a new regimen.

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