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HIV Co-morbidity | Open Access Journals
Journal of AIDS & Clinical Research

Journal of AIDS & Clinical Research

ISSN: 2155-6113

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HIV Co-morbidity

More and more people living with HIV and AIDS (PLHIV) have access to effective antiretroviral therapy and are living longer. As they age, they develop chronic age-related illnesses and are often at greater risk of these illnesses than people of similar HIV infection.
People living with HIV are more likely to have cardiovascular disease (CVD), for example, and are at increased risk for heart attacks, heart failure, stroke and sudden cardiac death. Several factors are thought to contribute to this increased risk, including direct damage to the heart muscle, persistent chronic inflammation and immune activation, side effects associated with antiretroviral therapy, and behavioral risk factors such as smoking. Many PHAs also have other risk factors for traditional CVD, including high blood pressure and high cholesterol.
Kidney disease is also commonly seen in PLWHIV. HIV infection of the kidneys, some HIV drugs, some drugs to treat opportunistic infections, and some pain relievers all contribute to this problem. High blood pressure and diabetes, the most common causes of kidney disease, are also often the cause of kidney disease in people living with HIV. In addition, PLHIV are more likely than their uninfected peers to exhibit symptoms of neurocognitive disease such as thinking and memory difficulties, but these problems occur less frequently in people with well-controlled HIV.

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Citations: 5264

Journal of AIDS & Clinical Research received 5264 citations as per Google Scholar report

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