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Endomyocardial FibrosisÂ | Open Access Journals

Journal of Coronary Heart Diseases

ISSN: 2684-6020

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Endomyocardial FibrosisÂ

Endomyocardial fibrosis (EMF) is a rare disease which is common in the tropical and subtropical regions of the developing world. It is characterized by fibrosis of the left ventricular and right ventricular endocardium which causes restrictive cardiomyopathy. The occurrence of frequent intracardiac thrombi in Endomyocardial fibrosis, and the embolization of these thrombi contributing to the morbidity is an established fact. Since previous studies on endomyocardial fibrosis revealed normal prothrombin time, clotting times, bleeding time, it was considered worthwhile to investigate whether an inherited deficiency of protein C contributed to thrombosis in these patients. It was observed that 5.55% and 44.4% of patients had normal profiles and Type 1 deficiency respectively, while 44.4% had Type II deficiency. This association between protein C deficiency and endomyocardial fibrosis may contribute to the formation of intracardiac thrombin in these patients.

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Journal of Coronary Heart Diseases received 15 citations as per Google Scholar report

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