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Pharmaceutical Regulatory Affairs: Open Access

Pharmaceutical Regulatory Affairs: Open Access

ISSN: 2167-7689

Open Access
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Drug Toxicology Peer Review Journals

Drug Toxicology is the science that deals with the amount of an agent in some living system which causes an adverse action. Toxicokinetics is the study of the body 's impacts on the toxin. The parent drug is also responsible for the toxic effects. However, the drug metabolites can be responsible for toxic effects. Checking of preclinical toxicity is a critical part of developing drugs. Checking of preclinical toxicity is a critical part of developing drugs. Usually, preliminary toxicity testing uses the values LD50 and NOAEL, LOAEL. With the Absorption, Distribution, Metabolism and Excretion related information, it is possible to predict concentration of toxin that reaches the injury site and the resulting damage. The key sources of toxicity / side effects of medications are: a. Foreseeable b. More probable c. Unforeseeable a. The predictable: overdosage at a primary site.

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Citations: 533

Pharmaceutical Regulatory Affairs: Open Access received 533 citations as per Google Scholar report

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