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Drug Susceptibility Patterns Of Tuberculosis | Open Access Journals
Journal of Microbiology and Pathology

Journal of Microbiology and Pathology

ISSN: 2952-8119

Open Access

Drug Susceptibility Patterns Of Tuberculosis

Mycobacterium tuberculosis drug sensitivity profiles. Out of a total of 135 Mycobacterium tuberculosis isolates, 68.9% (n = 93) were susceptible to the four drugs and 31.1% (n = 42) were resistant to all drugs. The highest resistance rate was for streptomycin (MS or S) (24.4%), followed by isoniazid (INH or H) (23%), rifampicin (RMP or R) ( 17.8%) and ethambutol (EMB or E) (15.6%). Out of a total of 135 positive culture TB cases, 21 (15.6%) were found to be MDR-TB. The prevalence of MDR-TB (19.4%) among previously treated cases was significantly higher than that of newly diagnosed cases (7.1%) and the difference was statistically significant. About 6.7% of the total culture-positive TB cases were multidrug-resistant TB (resistant to more than one drug but not to MDR-TB). Poly-resistant tuberculosis has not been reported in newly diagnosed tuberculosis patients.

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