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Bone Loss Open Scholarly Journals | Open Access Journals
Journal of Physiotherapy & Physical Rehabilitation

Journal of Physiotherapy & Physical Rehabilitation

ISSN: 2573-0312

Open Access

Bone Loss Open Scholarly Journals

Postmenopausal osteoporosis, a global public health problem, has been attributed for decades only to declining estrogen levels. Although FSH levels increase sharply in parallel, a direct effect of FSH on the skeleton has never been explored. We show that FSH is necessary for hypogonadic bone loss. Neither FSHβ null mice nor FSH receptors (FSHR) have bone loss despite severe hypogonadism. Bone mass is increased and osteoclastic resorption is decreased in FSHβ  haplo-sufficient mice with normal ovarian function, suggesting that the skeletal action of FSH is independent of estrogen. Osteoclasts and their precursors have FSHR coupled to Gi2α which activate MEK / Erk, NF-κB and Akt to cause improved formation and function of osteoclasts. We suggest that a high level of circulating FSH results in hypogonadic bone loss. In order to reduce these minerals and fruits plays a main role for strong bones.

Minerals play a crucial role in our body; one of the most important minerals is calcium. After all, it is responsible for supporting the development of teeth, bones, healthy muscles and much more. In addition, it is also one of the most abundant minerals in the human body, which is essential for health. According to Harvard University, the minimum daily calcium requirement is 1,000 milligrams per day for women under the age of 50 and 1,200 milligrams for women over the age of 50. Your food choices help you fill up with the optimal amount of calcium you need for basic functions. Although you may be familiar with the usual diet that contains calcium, which may include dairy products, some fruits contain calcium. We will use fruits rich in calcium that you can taste while making the most of these delights, but first of all, what role does calcium play in our body

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