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Articles On Ovarian Cancer | Open Access Journals
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Cancer Science & Therapy

ISSN: 1948-5956

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Articles On Ovarian Cancer

Ovarian cancer may be a sort of cancer that begins within the ovaries. The female reproductive system contains two ovaries, one on each side of the uterus. The ovaries — each about the dimensions of an almond — produce eggs (ova) also because the hormones estrogen and progesterone. Early-stage ovarian cancer, during which the disease is confined to the ovary, is more likely to be treated successfully.

Epithelial ovarian cancer generally presents at an advanced stage and is the most common cause of gynaecological cancer death. Treatment requires expert multidisciplinary care. Ovarian cancer is that the sixth commonest cancer worldwide among women in developed countries and therefore the most lethal of all gynecologic malignancies. Currently, most girls have advanced stage disease at the time of diagnosis. Despite aggressive surgery and chemotherapy, the prognosis for these women is poor, with a 5-year survival rate of less than 30%. This poor outcome is due in part to the lack of effective prevention and early detection strategies: when diagnosed at an early stage, the survival rate is approximately 85–90%. Thus, prevention and early detection are key to overcoming this disease. With the exception of oral contraceptives, there are no successful chemo preventive agents available. Bilateral oophorectomy has also been shown to reduce disease incidence, but the procedure has several drawbacks in terms of women’s health. Existing screening techniques (CA125, transvaginal ultrasound) have not been demonstrated to reduce morbidity or mortality. Thus, better prevention, detection and screening methods are urgently needed. As well, because of the virulent and usually fatal nature of the disease, most women with ovarian cancer live with fear of recurrence, which happens in about 85% of cases. Current treatments offer little hope and survival has remained virtually unchanged for almost three decades. New methods to prevent, detect and treat recurrence are urgently needed. Ovarian cancer is the most lethal gynecologic cancer. Less than one-half of patients survive for quite five years after diagnosis. Ovarian cancer affects women of all ages but is most ordinarily diagnosed after menopause. The strongest risk factors are advancing age and case history of ovarian and carcinoma. If results are suspicious for ovarian cancer, the patient should be mentioned a gynecologic oncologist.

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