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Adipose Tissue | Open Access Journals
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Journal of Tissue Science and Engineering

ISSN: 2157-7552

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Adipose Tissue

Adipose tissue (AT) is considered one of the largest endocrine organs in the body, as well as an active tissue for cellular reactions and metabolic homeostasis rather than an inert tissue for energy storage. The functional pleiotropism of AT is based on its ability to synthesize and release a large number of hormones, cytokines, extracellular matrix proteins, and growth and vasoactive factors, collectively called adipokines, that influence a variety of physiological and pathophysiological processes. AT dysfunctionality is clearly associated with the appearance of important pathologies that include obesity, type 2 diabetes, dyslipidemia or non-alcoholic fatty liver. The mechanisms underlying AT dysfunction include adipocyte hypertrophy and hyperplasia, AT inflammation, altered remodeling of the extracellular matrix, and fibrosis along with altered adipokine secretion. Recently, the potential role of brown AT as a secretory organ in protection against obesity has also been recognized.

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Citations: 807

Journal of Tissue Science and Engineering received 807 citations as per Google Scholar report

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