Journal of Clinical Research

Open Access

Current Issue

Volume 5, Issue 1 (2021)

    Short Communication Pages: 1 - 3

    Discussion on Tuberculosis.

    Michel Yan

    Tuberculosis (TB) is an irresistible sickness typically brought about by Mycobacterium tuberculosis (MTB) microscopic organisms. Tuberculosis by and large influences the lungs, In some cases TB effected different parts of the body. Most diseases show no manifestations, wherein case it is known as dormant tuberculosis. The exemplary side effects of dynamic TB are a persistent hack with blood-containing bodily fluid, fever, night sweats, and weight reduction. Tuberculosis is spread starting with one person to another person through the air when individuals who have dynamic TB in their lungs hack, spit, talk, or sniffle. Analysis of dynamic TB depends on chest X-beams, just as minuscule assessment and culture of body liquids. Finding of inert TB depends on the tuberculin skin test (TST) or blood tests.

    Short Communication Pages: 1 - 3

    Brief Note on Lipoma

    Royston Lee

    A lipoma is a kind tumor made of fat tissue. They are for the most part delicate to the touch, portable, and effortless. They typically happen simply under the skin, however sporadically might be more profound. Most are under 5 cm in size. Normal areas incorporate upper back, shoulders, and midsection. A couple of individuals have various lipomas. The reason is by and large muddled .Risk factors incorporate family ancestry, stoutness, and absence of activity. Determination is commonly founded on an actual test. At times clinical imaging or tissue biopsy is utilized to affirm the analysis. Treatment is regularly by perception or careful evacuation. Once in a while, the condition may repeat following expulsion, yet this can by and large be made do with rehash a medical procedure. They are not for the most part connected with a future danger of malignancy. Lipomas regularly happen in grown-ups somewhere in the range of 40 and 60 years of age. Males are more frequently influenced than females. They are the most widely recognized noncancerous delicate tissue tumor. The primary utilization of the expression "lipoma" to depict these tumors was in 1709.

    Mini Review Pages: 1 - 3

    Brief Discussion on Hepatitis

    Joseph Lee

    Hepatitis implies aggravation of the liver. The liver is an vital organ that measures supplements, channels the blood, and battles contaminations. At the point when the liver is aroused or harmed, its capacity can be influenced. Weighty liquor use, poisons, a few drugs, and certain ailments can cause hepatitis. (or)Hepatitis alludes to an incendiary state of the liver. It's generally brought about by a viral contamination, yet there are other potential reasons for hepatitis. Numerous diseases and conditions can cause irritation of the liver (hepatitis), yet certain infections cause about portion of all hepatitis in individuals. Infections that fundamentally assault the liver are called hepatitis infections. There are a few kinds of hepatitis infections including types A, B, C, D, E, and potentially G. Types A, B, and C are the most common. All hepatitis infections can cause intense hepatitis. Viral hepatitis types B and C can cause on going hepatitis.

    Editorial Note Pages: 1 - 2

    Development of Drug

    Sabastian David

    Medication disclosure and advancement are among the main translational science exercises that add to human wellbeing and prosperity. The medication disclosure and improvement measure from the lab seat through post advertising endorsement. A short history of medication revelation through the ages is incorporated to give point of view on the current circumstance and foreseen changes sooner rather than later.

    Short Commentry Pages: 1 - 2

    Short note on Blood Grouping

    Martin George

    A blood classification is an arrangement of blood (otherwise called a blood gathering), in view of the presence and nonappearance of antibodies and acquired antigenic substances on the outside of red platelets (RBCs). The Antigens consist of  proteins, sugars, glycoproteins, or glycolipids, contingent upon the blood bunch framework. A portion of the antigens are additionally present on the outside of different kinds of cells of different tissues.

    Volume 5, Issue 2 (2021)

      Commentary Pages: 1 - 2

      Going Digital Transformation of Oncology Clinical Research

      Roberto Jun Arai

      The COVID 19 pandemic pushed the oncology clinical research to an in-depth reengineering process. The article published at Contemporary Clinical Trials Communications [1], being part of the global literature of the World Health Organization (WHO) [2], Recommends several strategies to reduce and mitigate the risks in conducting oncology clinical research during the pandemic. Several actions led to decreased patient enrollment, and operational adjustments to comply with patient safety significantly affected the already lengthy study timelines. As a result, stakeholders are adopting technology-based approaches to reduce in-person patient visits to minimize COVID-19 dissemination and remote data monitoring.

      Editorial Pages: 1 - 1

      Discussion about Viral Disease Measles

      Azeem Helani

      Measles is an intense foundational viral disease with fever, respiratory contribution and side effects, and a rash. Measles can cause genuine inconveniences and even fatalities. Contamination presents deep rooted invulnerability. Measles is profoundly infectious and immunization preventable. Measles causes a red, smudged rash that generally shows up first on the face what's more, behind the ears, at that point spreads descending to the chest and back lastly to the feet. When very normal, measles can now quite often be forestalled with an antibody. Measles is caused by contamination with an infection from the paramyxovirus family. Infections are minuscule parasitic microorganisms. Whenever you've been tainted, the infection attacks have cells and utilizations cell segments to finish its life cycle. The measles infection contaminates the respiratory plot first. Be that as it may, it at last spreads to different pieces of the body through the circulation system. Measles is simply known to happen in people and not in different creatures.

      Commentary Pages: 1 - 1

      Short Note on Clinical Research

      Santra Andreya

      Clinical exploration is a sort of investigation of clinical or biomedical inquiries using human subjects. Clinical exploration examines don't really all include clinical medicines or trial treatments. Clinical examination can incorporate observational investigations, in which individuals are followed throughout some undefined time frame to decide wellbeing results. Clinical exploration may likewise be utilized to decide the handiness or wellbeing of another symptomatic methodology or medication treatment. Clinical examination considers are arranged ahead of time and follow a characterized convention. Epidemiologic examinations look at explicit populaces to explain how regularly a sickness happens or is found in a given gathering (the frequency and commonness), the individual factors that can cause or deteriorate infection movement, and the kinds of wellbeing and way of life choices that individuals make. Clinical preliminaries are one significant kind of clinical exploration.

      Short Communication Pages: 1 - 2

      Brief Discussion about Surgery

      Mohmmad Ismail

      Surgery procedure is a clinical or dental claim to fame that utilizes employable manual and instrumental methods on an individual to research or treat an obsessive condition like an illness or injury, to help improve materially capacity, appearance, or to fix undesirable burst regions. The demonstration of doing a medical procedure might be known as a surgery, activity, or essentially "medical procedure". In this specific circumstance, the action word "work" signifies to do a medical procedure. The modifier careful methods relating to a medical procedure, for example instruments or careful medical caretaker. The individual or subject on which the surgery procedure is performed can be an individual or a creature. A specialist is an individual who rehearses a medical procedure and a specialist's associate is an individual who rehearses careful help. A careful group is comprised of the specialist, the specialist's partner, an anesthetist, a flowing medical caretaker and a careful technologist. Medical procedure as a rule ranges from minutes to hours, yet it is ordinarily not a progressing or intermittent kind of therapy. The expression "medical procedure" can likewise allude to where medical procedure is performed, or, in British English, just the workplace of a doctor, dental specialist, or veterinarian.

      Review Article Pages: 1 - 4

      A Brief Review on the First Evaluation of a Synbiotic Food Supplement in Birch Pollen Allergic Patients in an Allergen Exposure Chamber

      Isabel Ojeda and Filippo Fassio

      Allergic Rhinitis (AR) is a “type 2“ inflammatory disease, caused by an immunoglobulin E (IgE)-mediated reaction to inhaled allergens and characterized by nasal symptoms. Pharmacologic treatment of AR mainly consists of oral/intranasal anti-histamines, intranasal glucocorticosteroids and Allergen-Specific Immunotherapy (AIT). When used correctly, these therapies are effective in most-but not in all-patients and can improve symptoms and Quality of Life (QOL); however, many patients show poor adherence to treatment, do not follow prescriptions, and coincidently experience side effects that lead to treatment cessation. Here, we briefly review and discuss recent findings from a proof-of-concept study about a synbiotic food supplement (Lactobacillus acidophilus NCFM, Bifidobacterium lactis BL-04 and Fructo-Oligosaccharides), which was evaluated in birch pollen allergic patients with AR, in a highly standardized setting of an Allergen Exposure Chamber (AEC). The study has demonstrated significant symptom improvement after the intake of the synbiotic food supplement. Both, the median TNSS was reduced by 50% (adjusted p-value=0.025) and the median TSS by 80% (adjusted p-value=0.0097), as well as the personal well-being of the patients was increased by 50%. In addition, the synbiotic food supplement revealed an excellent safety and tolerability profile. The present study is an excellent example that demonstrates efficacy for a specific synbiotic product and a superior tolerability and safety profile in the treatment of AR. It can be considered as an adjunct therapy for patients who do not improve with conventional medication for rhinitis, do not tolerate it or do not fit criteria for AIT. Evidence available to date guides us to consider probiotics/synbiotic as complementary treatment strategies in AR.

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