Department of Pulmonology, University of Health Sciences, Istanbul, Turkey
Research Article
Eosinophil Levels and Prognosis in Patients Hospitalized with COPD Exacerbation
Author(s): Hasan Furkan AVCI, Seyma Baslilar, Bengu Saylan, Gokce Kulah*, Tayfun Caliskan, Zafer Kartaloglu, Fatih Özçelik and Oğuzhan Okutan
Objective: The eosinophil count ≥ 300 cells/μL is known to be related to the increased risk for exacerbations in stable COPD. But the precise
'eosinophil threshold value' that can predict the disease course during exacerbations is still unclear. We aimed to determine a cut- off value for the
peripheral blood eosinophils during COPD exacerbations that will predict the outcome and recurrence.
Methods: 711 patients hospitalised due to COPD exacerbation between Oct 1st, 2016 and Jan1st, 2020 were analyzed retrospectively. The cut-off
values for Peripheral Blood Eosinophil Count (PBEC) and Ratio (PBER) predicting the risk for severe and recurrent exacerbations and, mortality
were determined.
Results: The cut-off values for PBEC and PBER were found as 170/μL and 1.15% (90.7% sensitivity, 28.3% specif.. Read More»
DOI:
10.37421/2161-105X.2025.15.717
Pulmonary & Respiratory Medicine received 1690 citations as per Google Scholar report