Virology: Current Research

ISSN: 2736-657X

Open Access

Yu Jin

Medical School of Nanjing University, Nanjing 210093, P.R. China

  • Mini Review   
    Immune Response to Human Rhinovirus C in Highly Differentiated Human Airway Epithelial Cells
    Author(s): Yu Jin* and Xin-hui Yuan

    Rhinovirus C (HRV-C) cannot be propagated in immortalized cells, and there is relatively little information on host cell responses to HRV-C infection. Human Bronchial Epithelial (HBE) cells are cultured at the Air-liquid Interface (ALI), which can form tight junctions, produce mucin, and differentiate to form cilia, representing an almost native cell system study HRV-C infections in vitro. In the present study, four strains of HRV-C from infectious clones and clinical specimens were infected with HBE-ALI cells. We found that they induced very similar immune responses, showing that the comparison basis was homogeneous... Read More»
    DOI: 10.37421/2736-657X.2022.6.146

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