Medicinal Chemistry

Department of Chemistry, Zagazig University, Zagazig 44523, Egypt

Publications

• Mini Review   
  Recent Advances in the Chemistry and Pharmacology of 2-Pyridone Scaffolds
  Author(s): Wesam Mouneir*
  
  Heterocycles play an important role in bioactive libraries and the pharmaceutical industry. They play an important role in our biological system, so researchers are still designing and discovering novel pharmacologically active molecules that may help to solve recent health issues. Nitrogenheterocycles are a common nucleus in many bioactive natural products and FDA-approved drugs, and they provide an important framework in drug discovery and agrochemical industries. Among all the common Nitrogen-heterocycles, 2-pyridone, a six-membered nitrogen ring, has piqued the interest of researchers due to its potent biological actions such as antibacterial, antitumor, antiinflammatory, antiproliferative, anti-hepatitis B virus, SARS-CoV-2 main protease inhibitor, and analgesic properties. According to a recent review, 2-pyridone structural motifs are important in the syn.. Read More»
  DOI: 10.37421/2161-0444.2022.12.656

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