Department of the Molecular Biology of the Cell Cycle, Institute of Molecular Biology “Roumen , Bulgarian Academy of Sciences, Akad. G. Bonchev Street, Bl. 21, Sofia 1113, Bulgaria
Research
Allelic Frequencies and Statistical Parameters Determination, for 16 Autosomal STR Markers Included in the NGM DetectTM PCR Amplification Kit, for the Bulgarian Population
Author(s): Plamen Iliev, Vera Djeliova, Ekaterina Angelova, Bogdan Mirchev, Milka Mileva, Atanas Hristov, Dimo Krastev and Aleksandar Apostolov*
In the presented study, the allelic frequencies and statistical parameters for 500 unrelated individuals from the 28 administrative regions of the
Republic of Bulgaria were determined for 16 autosomal genetic markers (STR), included in the NGM Detect™ PCR Amplification Kit (Applied
Biosystems), for the Bulgarian population. No deviations from Hardy-Weinberg equilibrium for the 16 studied loci were observed, except for a
deviation for the D8S1179 and FGA loci. The most polymorphic and informative for the Bulgarian population is the SE marker, with the next most
informative markers being: D1S1656, D12S391 and D18S51. For all 16 loci, the combined value Match Probability (MP) is 1.20e-21 and the power
of exclusion (PE) is 99.999999022%.
The results obtained from the DNA analysis have a very high identification value. Their interpretation is particularly .. Read More»
DOI:
10.37421/2472- 1026.2023.8.192
Journal of Forensic Medicine received 165 citations as per Google Scholar report
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