Immunochemistry & Immunopathology

Department of Immunology, Kindai University, Wakayama 649-6493, Japan

Publications

• Mini Review   
  Systemic Immune Response in the Pathogenesis of Cutaneous Leishmaniasis
  Author(s): Tindea Mechteleria*
  
  Cutaneous Leishmaniasis (CL) is a neglected tropical disease caused by protozoan parasites of the Leishmania genus. The disease manifests with diverse clinical presentations, ranging from self-healing cutaneous lesions to disfiguring mucocutaneous forms. The systemic immune response plays a pivotal role in the pathogenesis of CL, orchestrating a complex interplay between host defense mechanisms and parasite evasion strategies. This review provides a comprehensive overview of the systemic immune response in the context of CL pathogenesis, highlighting key immunological factors implicated in disease progression and outcome. Through a synthesis of current literature, this review elucidates the dynamic interactions between innate and adaptive immune components, cytokine networks and immune evasion mechanisms employed by Leishmania parasites. Insights gained from un.. Read More»
  DOI: 10.37421/2469-9756.2024.10.220

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