Heavy chain diseases (HCDs) are B-cell proliferative disorders. Heavy chain diseases characterized by production of abnormal, structurally incomplete and immunoglobulin heavy chains, without their corresponding light chains. In heavy chain disease often incomplete or truncated and a sharp, localized peak may not be seen on even the electrophoretic tracing of serum or urine. Gene mutations, deletions or insertions are caused due to the abnormal heavy chain diseases proteins. The heavy chain diseases are B-cell proliferative issue described by creation of strange, basically fragmented, immunoglobulin overwhelming chains without the relating light chains. The abnormal HCD proteins are the after effect of quality changes, cancellations, or insertions.
Related journals of Heavy Chain Diseases
Journal of Clinical & Cellular Immunology, Immunome Research, Journal of Vaccines & Vaccination, Journal of Allergy & Therapy, Journal of Clinical Pathology, Blood Journal of American Society of Hematology, Clinical Journal of the American Society of Nephrology