Journal of Clinical & Medical Genomics

Department of Virology, Philipps University Marburg, Marburg, Germany

Publications

• Mini Review   
  Demonstrate for the Omicron Variations Mouse Origin
  Author(s): Thomas Hoenen*
  
  The question of whether SARS-CoV-2 Omicron's primary origin occurred in humans or another animal host is raised by the rapid accumulation of mutations in the virus that enabled its flare-up. Here, we identified the 45 point alterations that Omicron acquired as a result of the B.1.1 genealogy's discrepancy. A possibility of host-hopping was suggested by our discovery that the Omicron spike protein grouping was exposed to more consistent positive choice than any other reported SARS-CoV-2 variants known to grow rigorously in human hosts. Although essentially not exactly the same as the range for infections that occurred in human patients, the sub-atomic range of modifications (i.e., the total recurrence of the 12 types of base substitutions) acquired by the progenitor of Omicron appeared to match the spectrum associated with infection progression... Read More»
  DOI: 10.37421/2472-128X.2023.11.243

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