Department of Pharmacy Practice, Jaya College of Paramedical Sciences, Chennai, India
Case Report
Author(s): Sabishruthi S, Vedha Pal JS*, Kavitha S, Deepak Paul DB and Ponsegaran V
Steven Johnson syndrome (SJS) is a life-threatening illness usually associated with usage of medicines, which causes drug interactions. SJS seems to be one of the lethal drug reactions. Herbal medications are also responsible for these syndromes; many medications have been reported to cause SJS. Even though only few cases are described in the literature. It has important impact on the public health in view of its high morbidity and mortality. It is a severe hypersensitive reaction which belongs to type IV hypersensitive reaction. SJS are considered to resemble erythema multiforme with mucosal involvement. It mainly affects oral mucosal cavity. A drug named Ginkgo biloba was prescribed to the patient affected with vitiligo and also treated with allopathic medications for fever and headache. It caused an herbal drug interaction which eventually induced Steven-johnson .. Read More»
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