Immunochemistry & Immunopathology

Department of Hematology, Tokyo University of Science, Tokyo 125-8585, Japan

Publications

• Mini Review   
  Advancing Immunotherapy: Harnessing Innate Immune Cells for Adult T-cell Leukemia-lymphoma Treatment
  Author(s): Rosa Murata*
  
  The relentless pursuit of effective treatments for Adult T-Cell Leukemia-Lymphoma (ATLL) has led to the exploration of innovative immunotherapeutic strategies. This study delves into the development of a novel approach, namely, the utilization of innate immune cells as a foundation for immunotherapy against ATLL. Harnessing the potent capabilities of these immune effectors, particularly Natural Killer (NK) cells and macrophages, offers a promising avenue for targeted and sustainable ATLL treatment. The research outlines the engineering and optimization of innate immune cells to enhance their specificity and cytotoxicity against ATLL cells while minimizing off-target effects. In-depth preclinical investigations demonstrate the efficacy of this immunotherapeutic strategy, highlighting its potential as a next-generation treatment modality for ATLL patients. The fi.. Read More»
  DOI: 10.37421/2469-9756.2023.9.211

  Abstract HTML PDF