GET THE APP

..

Malaria Control & Elimination

ISSN: 2470-6965

Open Access

P Patowary

Département of Pharmaceutical Chemistry, NETES Institute of Pharmaceutical Science, Kamrup-781125, India

Publications
  • Research Article   
    Tetrazole Moiety as a Pharmacophore in Medicinal Chemistry: A Review
    Author(s): P Patowary, B Deka* and D Bharali

    In present day scenario, tetrazole has gained increasing popularity due to its broad-spectrum of biological properties such as antitubercular, anticancer, antimalarial, antidiabetic, antifungal, anti-inflammatory activities etc. Tetrazole, beinga bioisostere of the carboxylic acid group can replace the carboxyl group in drugswhich can be utilized to increase the lipophilicity, bioavailability and to reduce theside effects of drugs. Many tetrazole containing compounds have already been used for the treatment of various diseases primarily due to their better pharmacokineticprofile and metabolic stability. Therefore, this heterocyclic tetrazole moiety having admirable biological, pharmaceutical and clinical applications can be considered as an important pharmacophore in the development of new drugs.The presentsurveyreviews the various approaches available for the synthesis of tetrazole d.. Read More»
    DOI: 10.37421/2470-6965.2021.10.167

    Abstract HTML PDF

Google Scholar citation report
Citations: 55

Malaria Control & Elimination received 55 citations as per Google Scholar report

Malaria Control & Elimination peer review process verified at publons

Indexed In

 
arrow_upward arrow_upward