IRCCS, Radiation Oncology Department, San Giovanni Rotondo, Italy
 Case Report   
								
																Cardiac Angiosarcoma after Chemo−Radiotherapy for Non−Hodgkin′s Lymphoma: A Case Report and Review of Literature 
																Author(s): M. Troiano*, E. E. Piazzolla, S. Cossa, A. Raguso, I. Troiano, P. Corsa, T. Munafò, F.P. Ricci, A. Parisi, F. Colangelo and S. Parisi             
								
																
						 Sarcomas in irradiated tissues are often considered second cancers and, among these, Angiosarcoma (AS) is an aggressive, malignant endothelialcell 
  tumour of vascular or lymphatic origin. AS can arise in any site of the body, but it very rarely occurs in major blood vessels or in the heart.
We report the case of 51-year old woman who developed a cardiac AS 20 year after chemoradiation therapy for bulky non-Hodgkin’s disease.
She was healthy until December 2013 when, because of persistent dyspnea, the family physician prescribed an echocardiographic exam that 
  evidenced an intracavitary left atrial mass that caused functional severe mitral stenosis. After complete surgical excision, the mass was confirmed 
  to be high grade AS. No residual tumor was detected by a post-operative cardiac magnetic resonance (MRI) and a positron emission tomography 
  (PET) s.. Read More»
						  
																DOI:
								10.37421/2684-4915.2023.7.250															  
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