Department of Pediatrics, Children's Hospital, Mohammed V University, Rabat, Morocco
 Case Report   
								
																Hepatic Cytolysis Induced by Percutaneous Application of Atractylis Gummifera: About a Case 
																Author(s): Oumaima El Qabissi*, Asmaa Alaoui Mdaghri, Yamna Kriouile and Aicha Chaibi             
								
																
						 Object: The thistle is an herbaceous plant known for its toxicity; it contains two diterpenic heterosides the Atractyloside and the carboxyatractyloside, 
  which are mitochondrial poisons, disrupting cellular respiration. The clinical manifestations of thistle poisoning are digestive, neurological and 
  hematological disorders. But there are also mild forms of poisoning. We report the case of a 9 month old female infant with no personal and family 
  medical pathological history, admitted to the PII service in a table of jet vomiting associated with consciousness disorders and hypoglycaemia, the 
  biochemical assessment found hepatic cytolysis. The history revealed the notion of local administration of thistle in powder form on diaper rash of 
  the infant. The outcome was favorable with symptomatic treatment based on N-acetyl cysteine.
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																DOI:
								10.37421/2684-4915.2023.6.249															  
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